Evaluation of the effects of hyaluronic acid on poly (3-hydroxybutyrate)/chitosan/carbon nanotubes electrospun scaffold: structure and mechanical properties

(2019) Evaluation of the effects of hyaluronic acid on poly (3-hydroxybutyrate)/chitosan/carbon nanotubes electrospun scaffold: structure and mechanical properties. Polymer-Plastics Technology and Materials. pp. 2031-2040. ISSN 2574-0881

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Official URL: WOS:000470320200001

Abstract

In this study, a combination of poly (3-hydroxybutyrate) (PHB), chitosan (Cs), multiwall carbon nanotubes (MWNTs), and different concentrations of Hyaluronic Acid (HA) were electrospun. The results showed that the produced nanofibers are uniform. Incorporation of HA, Cs and MWNTs reduced the water contact angle and made the scaffolds more hydrophilic. The porosity of the scaffolds was in the range of 80-88. The presence of MWNTs increased the tensile strength of scaffolds and different concentrations of HA had no much diverse effects. In conclusion, the PHB-Cs-MWNTs-HA 10 electrospun scaffold could be a good candidate for cartilage tissue engineering applications. GRAPHICS

Item Type: Article
Keywords: Carbon nanotubes cartilage tissue engineering chitosan hyaluronic acid poly (3-hydroxybutyrate) carbon nanotubes nanofibrous scaffolds chitosan scaffolds tissue regeneration principles Polymer Science
Subjects: QU Biochemistry. Cell Biology and Genetics > QU 135-144 Enzymes
Divisions: School of Advanced Technologies in Medicine > Department of Biomaterials, Nanotechnology and Tissue Engineering
Page Range: pp. 2031-2040
Journal or Publication Title: Polymer-Plastics Technology and Materials
Journal Index: ISI
Volume: 58
Number: 18
Identification Number: https://doi.org/10.1080/25740881.2019.1602645
ISSN: 2574-0881
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/11305

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