(2019) The Role of Environmental Disruptor Chemicals in the Development of Non Communicable Disease. In: Primordial Prevention of Non Communicable Disease. Advances in Experimental Medicine and Biology, 1121 . Springer International Publishing Ag, Cham, pp. 21-31. ISBN 978-3-030-10616-4; 978-3-030-10615-7
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Abstract
The increasing prevalence of non communicable diseases (NCDs) poses main challenges to global public health. Various environmental exposures to different chemicals and pollutants might interact with genetic and epigenetic mechanisms resulting in the development of NCDs. Among these environmental exposures, endocrine disrupting chemicals (EDCs) consist of a group of compounds with potential adverse health effects and the interference with the endocrine system. They are mostly used in food constituents, packaging industries and pesticides. Growing number of in vitro, in vivo, and epidemiological studies documented the link of EDC exposure with obesity, diabetes, and metabolic syndrome, which are the underlying factors for development of NCDs. Prevention of exposure to EDCs and reduction of their production should be underscored in strategies for primordial prevention of NCDs.
| Item Type: | Book Section |
|---|---|
| Keywords: | Endocrine disruptors Non communicable diseases Environment Metabolic disorder Obesity Diabetes bisphenol-a endocrine disruptors insulin-resistance metabolic syndrome human exposure risk-factors obese associations pesticides origins |
| Subjects: | WA Public Health > WA 670-847 Environmental Pollution. Sanitation |
| Divisions: | Research Institute for Primordial Prevention of Non-communicable Disease > Environment Research Center |
| Title of Book: | Primordial Prevention of Non Communicable Disease |
| Page Range: | pp. 21-31 |
| Volume: | 1121 |
| Publisher: | Springer International Publishing Ag |
| Identification Number: | https://doi.org/10.1007/978-3-030-10616-4₃ |
| ISBN: | 978-3-030-10616-4; 978-3-030-10615-7 |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/11512 |
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