(2020) The journey of multifunctional bone scaffolds fabricated from traditional toward modern techniques. Bio-Design and Manufacturing. pp. 281-306. ISSN 2096-5524
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Abstract
As a bone scaffold, meeting all basic requirements besides dealing with other bone-related issues-bone cancer and accelerated regeneration-is not expected from traditional scaffolds, but a newer class of scaffolds called multifunctional. From a clinical point of view, being a multifunctional scaffold means reducing in healing time, direct costs-medicine, surgery, and hospitalization-and indirect costs-loss of mobility, losing job, and pain. The main aim of the present review is following the multifunctional bone scaffolds trend to deal with both bone regeneration and cancer therapy. Special consideration is given to different fabrication techniques which have been applied to yield these materials spanning from traditional to modern ones. Moreover, the hierarchical structure of bone plus bone cancers and available medicines to them are introduced to familiarize the potential reader of review with the pluri-disciplinary essence of the field. Eventually, a brief discussion relating to the future trend of these materials is provided.
Item Type: | Article |
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Keywords: | Multifunctional scaffolds Bone cancer Fabrication techniques Bone tissue regeneration BIOACTIVE GLASS SCAFFOLDS SPACE HOLDER METHOD MESOPOROUS MAGNESIUM-SILICATE SOL-GEL SYNTHESIS DRUG-DELIVERY MECHANICAL-PROPERTIES POROUS TITANIUM MAGNETIC NANOPARTICLES HIERARCHICAL STRUCTURE CELL-DIFFERENTIATION |
Subjects: | QZ Pathology > QZ 200-380 Neoplasms W General Medicine. Health Professions > W 82-83.1 Biomedical Technology WE Musculoskeletal System |
Divisions: | Biosensor research center School of Advanced Technologies in Medicine > Department of Biomaterials, Nanotechnology and Tissue Engineering |
Page Range: | pp. 281-306 |
Journal or Publication Title: | Bio-Design and Manufacturing |
Journal Index: | ISI |
Volume: | 3 |
Number: | 4 |
Identification Number: | https://doi.org/10.1007/s42242-020-00094-4 |
ISSN: | 2096-5524 |
Depositing User: | Zahra Otroj |
URI: | http://eprints.mui.ac.ir/id/eprint/12328 |
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