(2020) Quercetin with the potential effect on allergic diseases. Allergy Asthma and Clinical Immunology. ISSN 1710-1492
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Abstract
Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ss2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD).
| Item Type: | Article |
|---|---|
| Keywords: | Quercetin Allergy Asthma ATOPIC-DERMATITIS IN-VIVO INFLAMMATION POLYPHENOLS EXPRESSION EPITHELIUM RHINITIS MODEL |
| Subjects: | QW Microbiology and Immunology > QW 501-949 Immunology |
| Divisions: | Cardiovascular Research Institute > Applied Physiology Research Center Cardiovascular Research Institute > Isfahan Cardiovascular Research Center Faculty of Medicine > Department of Basic Science > Immunology Department |
| Journal or Publication Title: | Allergy Asthma and Clinical Immunology |
| Journal Index: | ISI |
| Volume: | 16 |
| Number: | 1 |
| Identification Number: | https://doi.org/10.1186/s13223-020-00434-0 |
| ISSN: | 1710-1492 |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/12815 |
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