Determine the efficacy of antibiotic prophylaxis and specific antibiotic regimens in dental implant placement for the prevention of postoperative infection (POI) in children: A systematic review and meta-analysis

Abstract

Background and aim: Conflicting proposals on antibiotic prophylaxis in dental implant placement reveal the require for investigation of current writing on the subject and re-evaluation of related dangers and benefits. So, the aim of this systematic review and meta-analysis was determine the efficacy of antibiotic prophylaxis and specific antibiotic regimens in dental implant placement for prevention of POI in children and adults. Method: MEDLINE, PubMed, Cochrane Library, Embase, ISI, google scholar were used as electronic databases to perform a systematic literature between 2015 to 2019. A commercially available software program (Endnote X9) was used for electronic title management. Searches were performed with keywords, “antibiotic”, “prophylaxis”,” antibiotic regimens”,” dental implant”, “implant” “post-operative infection OR POI”, “children”, “pediatric dentistry”, “adults”,” healthy patients”. The present systematic review was performed based on the main consideration of PRISMA Statement–Preferred Reporting Items for Systematic Reviews and Meta-analysis Result: All antibiotic regimens group (RR 2.87, 95 CI 0.16 to 52.74), pre-operative only antibiotic group (RR 4.82, 95 CI 0.24 to 98.89), pre- and post-operative antibiotic group (RR 4.55, 95 CI 0.22 to 93.38). Conclusion: Antibiotic prophylaxis may not be shown for the anticipation of POIs following dental implant placement in generally healthy patients. © 2020, Advanced Scientific Research. All rights reserved.