(2021) Can coronavirus disease 2019 (COVID-19) trigger exacerbation of multiple sclerosis? A retrospective study. Multiple Sclerosis and Related Disorders. ISSN 2211-0348
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Abstract
The effect of coronavirus disease (COVID-19) on the risk of relapse in multiple sclerosis (MS) have been unknown. In this retrospective study of 41 relapsing-remitting MS patients, number of relapses in pre-defined at risk-period (ARP) was compared with the previous two years. During the previous two years, a total of 32 attacks was reported, which 5 (15.6) were during the at-risk period. After adjusting for age and sex, there was an increased risk of attack during ARP compared to the previous two years (RR: 2.566, 95CI: 1.075-6.124, P=0.034). Our preliminary study suggested that COVID-19 can trigger exacerbation of MS.
| Item Type: | Article |
|---|---|
| Keywords: | Multiple sclerosis Coronavirus Infection Relapse Exacerbation INFECTIONS |
| Subjects: | WL Nervous System WL Nervous System > WL 200-405 Central Nervous System. Disorders. Therapeutics |
| Divisions: | Faculty of Medicine > Departments of Clinical Sciences > Department of Neurology Isfahan Neurosciences Research Center |
| Journal or Publication Title: | Multiple Sclerosis and Related Disorders |
| Journal Index: | ISI |
| Volume: | 52 |
| Identification Number: | https://doi.org/10.1016/j.msard.2021.102947 |
| ISSN: | 2211-0348 |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/14150 |
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