Electrocardiogram Changes in Patients With Acute Ethanol Poisoning

Abstract

Background: Alcohol consumption leads to a significant number of deaths, mostly in men, worldwide. Considering the effect of ethanol toxicity on the heart, we studied various Electrocardiographic (ECG) changes in patients with acute ethanol poisoning. Methods: A cross-sectional study was performed on patients admitted to Khorshid Hospital (affiliated to Isfahan University of Medical Sciences) due to ethanol poisoning. All 15- to 50-year-old patients with acute ethanol intoxication were included in the study (N=250). The patients' information, including the demographic characteristics, clinical manifestations, and ECG changes were recorded and analyzed. Different variables were compared between the patients with or without ECG changes. Results: Most of the research patients (n=208) were men (83.82). The Mean +/- SD age of the study patients was 26.8 +/- 8.87 years. About 54.8 of the patients presented abnormal ECG. The changes in ECG were not significantly different based on the demographic characterisfic and clinical manifestations. The time interval between ethanol consumption and admission was significantly higher in patients with abnormal ECG, compared to those with normal ECG (Mean +/- SD: 7.09 +/- 10.67 vs. 4.77 +/- 4.54 hours, respectively) (P=0.03). Results: Most of the research patients (n=208) were men (83.82). The Mean +/- SD age of the study patients was 26.8 +/- 8.87 years. About 54.8 of the patients presented abnormal ECG. The changes in ECG were not significantly different based on the demographic characterisfic and clinical manifestations. The time interval between ethanol consumption and admission was significantly higher in patients with abnormal ECG, compared to those with normal ECG (Mean +/- SD: 7.09 +/- 10.67 vs. 4.77 +/- 4.54 hours, respectively) (P=0.03). Conclusion: ECG changes are common in patients with ethanol poisoning. The time interval between ethanol consumption to hospital admission may be an important factor in the occurrence of ECG changes.