In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives

(2017) In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives. Antimicrobial Agents and Chemotherapy. ISSN 0066-4804

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Abstract

The in vitro activities of novel azoles compared to those of five antifungal drugs against clinical (n = 28) and environmental ( n = 102) isolates of black mold and melanized yeast were determined. Luliconazole and lanoconazole had the lowest geometric mean MICs, followed by efinaconazole, against tested isolates compared to the other drugs. Therefore, it appears that these new imidazole and triazole drugs are promising candidates for the treatment of infections due to melanized fungi and their relatives.

Item Type: Article
Keywords: melanized fungi in vitro mic efinaconazole lanoconazole luliconazole cutaneous candidiasis therapeutic-efficacy guinea-pigs agent imidazole susceptibility infections
Divisions: Faculty of Medicine > Department of Basic Science > Department of Parasitology and Mycology
Journal or Publication Title: Antimicrobial Agents and Chemotherapy
Journal Index: ISI
Volume: 61
Number: 11
Identification Number: ARTN e00635-17 10.1128/AAC.00635-17
ISSN: 0066-4804
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mui.ac.ir/id/eprint/143

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