(2021) COVID-19-associated coagulopathy: a concise review on pathogenesis and clinical implications. Infez Med. pp. 1-9. ISSN 1124-9390 (Print) 1124-9390
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Abstract
In this review, we summarize the possible mechanisms of COVID-19-associated coagulopathy and compare its features to other similar conditions. The recent COVID-19 pandemic has caused enormous mortality and morbidity worldwide. It is important to note that COVID-19-associated thrombotic events play a huge role in the morbidity of this disease. Interestingly, it has been observed that this complication may occur despite prophylactic anticoagulant therapy. Recent studies on COVID-19-associated coagulopathy revealed that the COVID-19-associated hypercoagulability is more frequently observed among those with a severe course of the disease. Various mechanisms have been suggested as explanations for this condition and possible underlying etiologies.
| Item Type: | Article |
|---|---|
| Keywords: | Angiotensin-Converting Enzyme 2/metabolism Anticoagulants/administration & dosage/adverse effects Blood Coagulation Disorders/*etiology/metabolism COVID-19/blood/*complications Endothelium, Vascular/metabolism Fibrin Fibrinogen Degradation Products/metabolism Hemostasis Heparin/adverse effects Humans Interleukin-10/blood Interleukin-6/blood Receptors, Interleukin-2/blood *SARS-CoV-2/pathogenicity Thrombophilia/etiology Thrombosis/etiology Tumor Necrosis Factor-alpha/blood Virus Internalization |
| Page Range: | pp. 1-9 |
| Journal or Publication Title: | Infez Med |
| Journal Index: | Pubmed |
| Volume: | 29 |
| Number: | 1 |
| ISSN: | 1124-9390 (Print) 1124-9390 |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/14747 |
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