Ocular perfusion pressure in patients with acute ischemic central retinal vein obstruction in comparing with control group

Abstract

Background: Ocular perfusion pressure (OPP) can be used as a predictive factor for the severity and prognosis of eye diseases. The aim of this study was to evaluate the rate of ocular perfusion pressure in ischemic retinal vein ischemia. Methods: This cross-sectional study was performed in two groups of 44 patients (patient and control) in Feyz hospital, Isfahan, Iran. The diagnosis of acute central retinal vein occlusion (CRVO) was made on the basis of clinical criteria. Effective risk factors and mean arterial pressure (MAP), OPP, intraocular pressure (IOP) were measured. The results were analyzed using SPPS software. Findings: OPP was 59.38 ± 4.35 in patients with CRVO and 53.49 ± 6.45 in the control group, and a significant difference was observed (P = 0.004). Intraocular pressure was 15.15 ± 2.61 and 13.77 ± 2.12 in the CRVO and control groups, respectively, with a significant difference (P = 0.008). Conclusion: OPP and also the IOP were significantly higher in the CRVO group. Increasing of OPP can be due to a relative increase in blood pressure (BP) or a relative increase in IOP, each of which alone or together can lead to vascular events. Ocular perfusion pressure is used as a risk factor of CRVO. © 2021 Isfahan University of Medical Sciences(IUMS). All rights reserved.