The Clinical Approach toward Hereditary Persistence of Fetal Hemoglobin: A Case Report

(2022) The Clinical Approach toward Hereditary Persistence of Fetal Hemoglobin: A Case Report. IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY. pp. 364-368. ISSN 1735-1502 1735-5249 J9 - IRAN J ALLERGY ASTHM

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Abstract

Fetal hemoglobin is the principal hemoglobin in the human fetus, and the adult levels of fetal hemoglobin (HbF) are less than 1 of total hemoglobin. A steady increase of HbF in patients with hereditary persistence of fetal hemoglobin (HPFH) is associated with complications. The present report describes HPFH in a 26-year-old man with emphasis on its hemoglobin electrophoresis. The patient was admitted with complaints of recurrent weakness and lethargy, weight loss, abdominal pain, and dyspepsia. Splenectomy was planned due to massive splenomegaly and gastrointestinal complications. Ultimately, electrophoresis confirmed the diagnosis of HPFH.

Item Type: Article
Keywords: Blood protein electrophoresis Fetal hemoglobin Hemoglobinopathies BETA-THALASSEMIA DIAGNOSIS
Page Range: pp. 364-368
Journal or Publication Title: IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY
Journal Index: ISI
Volume: 21
Number: 3
Identification Number: https://doi.org/10.18502/ijaai.v21i3.9810
ISSN: 1735-1502 1735-5249 J9 - IRAN J ALLERGY ASTHM
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/15875

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