(2022) Therapeutic potential of silymarin as a natural iron-chelating agent in beta-thalassemia intermedia. CLINICAL CASE REPORTS. ISSN 2050-0904 J9 - CLIN CASE REP
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Abstract
Abnormal iron accumulation in vital organs is one of the major complications of beta-thalassemia intermedia (beta-TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of beta-TI patients. This finding suggests silymarin as a safe and effective natural iron-chelating agent for the treatment of iron-overloaded conditions.
| Item Type: | Article |
|---|---|
| Keywords: | ferritin iron chelator liver milk thistle silymarin thalassemia RANDOMIZED DOUBLE-BLIND |
| Journal or Publication Title: | CLINICAL CASE REPORTS |
| Journal Index: | ISI |
| Volume: | 10 |
| Number: | 1 |
| Identification Number: | https://doi.org/10.1002/ccr3.5293 |
| ISSN: | 2050-0904 J9 - CLIN CASE REP |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/15894 |
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