Emerging roles for lncRNA-NEAT1 in colorectal cancer

(2022) Emerging roles for lncRNA-NEAT1 in colorectal cancer. CANCER CELL INTERNATIONAL. ISSN 1475-2867 J9 - CANCER CELL INT

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Abstract

Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular and translational medicine. Emerging evidence has supported that lncRNAs can regulate cell cycle of CRC cells. LncRNA NEAT1 has been verified to participate in colon cancer development and progression. NEAT1 as a competing endogenous RNA could suppress the expression of miRNAs, and then regulate molecules downstream of these miRNAs. In this review, we summarized emerging roles of NEAT1 in CRC cells.

Item Type: Article
Keywords: Colorectal cancer lncRNAs NEAT1 Progression LONG NONCODING RNA 5-FU SENSITIVITY COLON-CANCER CELLS INCREASES APOPTOSIS AUTOPHAGY INVASION
Journal or Publication Title: CANCER CELL INTERNATIONAL
Journal Index: ISI
Volume: 22
Number: 1
Identification Number: https://doi.org/10.1186/s12935-022-02627-6
ISSN: 1475-2867 J9 - CANCER CELL INT
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/16063

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