(2022) Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways. INFLAMMOPHARMACOLOGY. pp. 1-7. ISSN 0925-4692 (Print) 0925-4692
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Abstract
Hesperetin, an aglycone metabolite of hesperidin with high bioavailability, recently gained attention due to its anti-COVID-19 and anti-cancer properties. Multiple studies revealed that cancer patients are prone to experience a severe form of COVID-19 and higher mortality risk. In addition, studies suggested that COVID-19 can potentially lead to cancer progression through multiple mechanisms. This study proposes that hesperetin not only can be used as an anti-COVID-19 agent but also can reduce the risk of multiple cancer progression by suppressing several intracellular signaling pathways in cancer patients with COVID-19. Therefore, in this review, we attempted to provide evidence demonstrating anti-COVID-19/cancer properties of hesperetin with several mechanisms.
| Item Type: | Article |
|---|---|
| Keywords: | Covid-19 Cancer Hesperetin SARS-CoV-2 Signaling pathways |
| Page Range: | pp. 1-7 |
| Journal or Publication Title: | INFLAMMOPHARMACOLOGY |
| Journal Index: | Pubmed |
| Identification Number: | https://doi.org/10.1007/s10787-022-01054-3 |
| ISSN: | 0925-4692 (Print) 0925-4692 |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/16688 |
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