(2017) Comparison of Different Obesity Indices for Predicting Incident Hypertension. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension. pp. 157-166. ISSN 1179-1985 (Electronic) 1120-9879 (Linking)
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Abstract
INTRODUCTION: Obesity is well recognized to be an important risk factor for hypertension (HTN), but it is not clear which obesity indices have stronger association with HTN. AIM: To evaluate the ability of different obesity indices, including visceral adiposity index (VAI), hypertriglyceridemic-waist (HTGW) phenotype, a body shape index (ABSI), body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and waist-to-hip ratio (WHR) as possible hypertension (HTN) predictor in a high-risk population. METHODS: Seven years follow-up data in first-degree relatives of consecutive patients with type 2 diabetes aged 30-70 years without diabetes and HTN with at least one follow-up examination (n = 1417) were analysed. Discriminatory capabilities were examined using the receiver operating characteristic (ROC) curve. Logistic regression analysis was performed to determine the strength of association between obesity indices and HTN. RESULTS: Among the indices, the highest quintile compared with the lowest quintile of WHtR and WC was more strongly associated with HTN in age and sex adjusted models odds ratio (95% CI); WHtR: 4.02 (2.36, 6.85) and WC: 3.26 (2.05, 5.20). Those with HTGW phenotype was 2.3 (1.54, 3.35) times more likely to develop HTN than those with normal WC normal triglyceride. On ROC curve analysis, WHtR (63.1%; 59.6, 66.7) and WC (61.7%, 58.0, 65.4) had the higher area under the ROC. CONCLUSIONS: Although higher values of VAI, BMI, WHR and HTGW were associated with the risk of HTN, WHtR and WC was more strongly associated with the development of HTN, while the ABSI showed weaker association.
Item Type: | Article |
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Keywords: | Adiposity Adult Area Under Curve *Blood Pressure Body Mass Index Chi-Square Distribution Diabetes Mellitus, Type 2/epidemiology Female Humans Hypertension/diagnosis/*epidemiology/physiopathology Hypertriglyceridemic Waist Incidence Intra-Abdominal Fat/physiopathology Iran/epidemiology Logistic Models Longitudinal Studies Male Middle Aged Multivariate Analysis Obesity/*diagnosis/*epidemiology/physiopathology Odds Ratio Phenotype Predictive Value of Tests Prognosis ROC Curve Risk Assessment Risk Factors Time Factors Waist Circumference Waist-Height Ratio Waist-Hip Ratio A body shape index Anthropometry First-degree relatives Hypertension Hypertriglyceridemic-waist Risk factor Visceral adiposity index |
Divisions: | Faculty of Health > Department of Epidemiology and Biostatistics Isfahan Endocrine and Metabolism Research Center |
Page Range: | pp. 157-166 |
Journal or Publication Title: | High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension |
Journal Index: | Pubmed |
Volume: | 24 |
Number: | 2 |
Identification Number: | https://doi.org/10.1007/s40292-017-0186-3 |
ISSN: | 1179-1985 (Electronic) 1120-9879 (Linking) |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.mui.ac.ir/id/eprint/1685 |
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