Longitudinally extensive transverse myelitis as a sign of multisystem inflammatory syndrome following COVID-19 infection: A pediatric case report

(2021) Longitudinally extensive transverse myelitis as a sign of multisystem inflammatory syndrome following COVID-19 infection: A pediatric case report. JOURNAL OF NEUROIMMUNOLOGY. ISSN 0165-5728 1872-8421 J9 - J NEUROIMMUNOL

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Abstract

COVID-19 infection can cause inflammatory reactions that could involve several organs. In the pediatric population, Multi-System Inflammatory Syndrome in Children (MIS-C) has been reported as one of the consequences of COVID-19. We report a unique pediatric COVID-19 patient with MIS-C, associated with paralysis of the extremities. MRI showed abnormal signal in the cervical spinal cord compatible with transverse myelitis. Methylprednisolone and IVIG were administered, without significant symptom improvement. As a next step, Infliximab was tried for her, and she responded remarkably well to this treatment. Infliximab may be considered as a treatment option in COVID-19 patients with transverse myelitis.

Item Type: Article
Keywords: COVID-19 Multi-System Inflammatory Syndrome Transverse myelitis Pediatric Infliximab Immunotherapy DIAGNOSIS CHILDREN
Journal or Publication Title: JOURNAL OF NEUROIMMUNOLOGY
Journal Index: ISI
Volume: 360
Identification Number: https://doi.org/10.1016/j.jneuroim.2021.577704
ISSN: 0165-5728 1872-8421 J9 - J NEUROIMMUNOL
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/17455

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