Introduction: Hot and Cold Theory, the Path Towards Personalized Medicine

Abstract

In traditional medicines, the concept of "hot and cold theory" or temperament evolved based on thousands of years of precise observation of individuals' differences to provide efficacious personalized treatments. Based on the hot and cold theory, human body organs have extensive interactions forming a complex system in a dynamic equilibrium named temperament, Dosha, constitution, or Mizaj. This equilibrium is different between individuals and is affected by genetics, environment, and lifestyle. Deviation from this balance state on the coldness-hotness spectrum can predispose one to various diseases. The goal of prevention and treatment is to maintain or revive the body system's status towards that person's original equilibrium.