Human bocavirus single infections and co-infections with Respiratory Syncytial Virus and Rotavirus in children with acute respiratory or gastrointestinal infections

Abstract

Human bocavirus (HBoV) has been reported in the respiratory and stool samples in pediatric infections. The aims of study were to find the correlation between of HBoV single and co-infections in respiratory and gastrointestinal cases. This report was in the period 2017-2018 that involved children less than 3 years old, who admitted to Mofid Children's Hospital in the center of Iran in Tehran. At first, the respiratory and stool samples tested for the RSV and Rotavirus by RT-PCR respectively and then all samples tested for the NP-1 gene of HBoV by PCR. The 67 out of 500 respiratory samples (13.4) and 72 out of 500 stool samples (14.4) were positive of HBoV. The 44 (65.6) of respiratory samples have co-infection with RSV and 45 (62.5) of stool samples have co-infection with Rotavirus. The HBoV infections emerged often as co-infections with other viral agents. © 2019 Greek Society of Microbiology Ascent Ltd. All rights reserved.