Effects of green tea consumption on the biochemical, inflammatory and antioxidant parameters in patients with coronary artery disease

Abstract

Introduction: Coronary Artery disease is one of the major reasons of death and disability. The Aim of this study is to determine the Effectiveness of green tea on biochemical and inflammatory and antioxidant parameters in patients with coronary artery disease. Methods: This clinical trial study was done in Rafsanjan city, the south east of Iran, from October 2016 to March 2017. Seventy two patients with coronary artery disease were enrolled in two case and control groups. The case group was received 4 green tea bags daily during 8 weeks. Anthropometric, biochemical and antioxidant evaluation and blood pressure measurement in two groups before and after the intervention were done. Antioxidants intake and diet change during intervention were evaluated. Results: Mean and standard deviation of age and weight of patients in case group was 60.78±11.78 years and 73.03± 11.62 kg and in control group was 62.6±10.8 years and 74.03±12.2 kg. Both groups were adjusted in terms of age, BMI, gender and there was no significant difference in educational level, history of heart disease, addiction, smoking, and dietary antioxidants intake. Green tea intake caused a significant decrease in weight, body mass index, Waist circumference, triglyceride, MDA, IL6, fasting blood sugar, systolic and diastolic blood pressure (P<0.05). The mean of HDL and TAC were significantly increased after intervention (P<0.05). Conclusion: Green tea consumption in patient with CAD disease for 8 weeks had beneficial effects on weight loss, BMI and waist circumference. It improved lipid profile, antioxidant parameters and decrease systolic and diastolic blood pressure in patients. © 2018, Shahroud University of Medical Sciences. All rights reserved.