(2017) Gastrointestinal cancers. In: Cancer Genetics and Psychotherapy. Springer International Publishing, pp. 589-625. ISBN 9783319645506 (ISBN); 9783319645483 (ISBN)
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Abstract
Gastrointestinal cancers (GI) are an important category of cancers. This chapter reviews the updates on different aspects of GI cancers including pathophysiology, classification, genetics, genotype-phenotype correlations, screening, surveillance, genetic counseling, testing strategies, management and individualized medicine of esophageal cancers (squamous cell carcinoma and adenocarcinoma), gastric cancer (intestinal and diffuse subtypes), and colorectal cancers (CRCs) (with focus on Lynch syndrome and adenomatous polyposis colon cancer which are two common hereditary form of CRCs). Our current understanding of different aspects of GI cancers and future directions especially in the issues of genetic profiling and targeted therapies in GI cancers are tried to be address in this chapter. © Springer International Publishing AG 2017. All rights reserved.
| Item Type: | Book Section |
|---|---|
| Keywords: | Colorectal cancer Esophageal cancer Familial adenomatous polyposis Gastric cancer Gastrointestinal cancer Hereditary non-polyposis HNPCC Lynch syndrome MSI analysis |
| Divisions: | Faculty of Medicine > Department of Basic Science > Department of Molecular Medicine and Genetics |
| Title of Book: | Cancer Genetics and Psychotherapy |
| Page Range: | pp. 589-625 |
| Publisher: | Springer International Publishing |
| Identification Number: | https://doi.org/10.1007/978-3-319-64550-6₁₂ |
| ISBN: | 9783319645506 (ISBN); 9783319645483 (ISBN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.mui.ac.ir/id/eprint/1845 |
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