Book Section #1846

Abstract

Endocrine cancers: Endocrine cancers are an important category of cancers. The frequencies of different types of endocrine cancers vary greatly. While thyroid cancer subtypes constitute approximately 1 of new cancer cases in the United States each year, prostate cancer assumes a top rank after cutaneous cancers; one in six white men and one in five African-American men are diagnosed with prostate cancer. This chapter reviews the updates on different aspects of endocrine cancers including pathophysiology, classification, genetics, genotype-phenotype correlations, screening, surveillance, genetic counseling, testing strategies, management and individualized medicine of Type 1 multiple endocrine neoplasia (MEN1), Type 2 multiple endocrine neoplasia (MEN2), different types of thyroid cancer, and prostate cancer. Thyroid cancer: This section describes the thyroid cancer. A general pathophysiology and classification will be detailed on solitary thyroid nodule, papillary carcinoma, follicular carcinoma, Hürthle cell carcinomas, medullary thyroid carcinoma and Anaplastic carcinoma as well as "other" thyroid carcinomas. Genetics, genotype-phenotype correlations, screening and surveillance, genetic counseling and testing strategies and management and individualized medicine are discussed separately for each cancer type. © Springer International Publishing AG 2017. All rights reserved.