Prognostic factors of outcome in children with acute respiratory distress syndrome

Abstract

Background: Available data about the prognostic factors in children with acute respiratory distress syndrome (ARDS) are controversial. The goal of our study was to determine the prognostic factors of outcome in children with ARDS. Methods: In this cross sectional study, 88 children with ARDS in Imam Hossein children hospital, Isfahan, Iran, were recruited in a period of 2 years. According to outcomes, patient allocated into two groups of deceased and discharged. Patients’ characteristics including age and gender, underlying disorders, parameters of mechanical ventilations, arterial blood gas, organ involvement, and pediatric risk of mortality (PRISM) score were compared between the two groups. Findings: Higher PRISM score, higher positive end-expiratory pressure (PEEP) and peak inspiratory pressure (PIP), and presence of other organ involvement were predictive factors of mortality (P < 0.05). However, age, gender, length of stay, weight, partial pressure of oxygen (PaO2), and partial pressure of carbon dioxide (PaCO2) were not different significantly between the two groups (P > 0.05). Conclusion: The PRISM score was a reliable predictor for mortality rate among the patients with ARDS in pediatric intensive care unit (PICU). © 2017, Isfahan University of Medical Sciences(IUMS). All rights reserved.