AC-Mode of Chemotherapy as a Trigger of Cardiac Syndrome X: A Case Study Zinaida Jndoyanj

Abstract

In the period of dynamic development of pharmacological possibilities in the modern oncology, unfortunately, the issue of cardiotoxicity of chemo-therapy did not lost its urgent value. Cardiotoxicity implies structural and functional myocardial alter-ation, together with an increase in the concentration of highly sensitive markers of myocardial necrosis, in particular T and I troponins, and N-terminal pro-BNP, as well as with a subclinical or clinical decrease in the LVEF. It is noteworthy that cardiotoxicity is manifested not only by the development of anthracy-cline cardiomyopathy with a high risk of convention into heart failure. It also can cause various cardiovas-cular pathologies, in particular cardiac syndrome X.This study described chemotherapy-induced microvas-cular angina in 23-year-old otherwise heathy woman. The diagnosis is challenging for doctors, since micro-vascular flow may be only detected by using functional test. (Curr Probl Cardiol 2022;47:100994.)