Antibiotic resistance pattern of <i>Helicobacter pylori</i> strains isolated from patients in Isfahan, Iran

Abstract

Background: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. Materials and Methods: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method. Reaults: Of 96 samples, 50 samples (53) were positive for H. pylori. The rates of antibiotic resistance were as follows: amoxicillin, 6; azithromycin, 20; furazolidone, 22; levofloxacin, 16; metronidazole, 20; rifampin, 12; and tetracycline, 22. Conclusion: H. pylori strains in our area have high rates of resistance to azithromycin, levofloxacin, metronidazole, tetracycline, and furazolidone.