Pharmacotherapeutic potential of pomegranate in age-related neurological disorders

(2022) Pharmacotherapeutic potential of pomegranate in age-related neurological disorders. Frontiers in Aging Neuroscience. p. 27. ISSN 1663-4365

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Abstract

Age-related neurological disorders AND include neurodegenerative diseases NDDs such as Alzheimer's disease AD and Parkinson's disease PD, which are the most prevalent types of dementia in the elderly. It also includes other illnesses such as migraine and epilepsy. ANDs are multifactorial, but aging is their major risk factor. The most frequent and vital pathological features of AND are oxidative stress, inflammation, and accumulation of misfolded proteins. As AND brain damage is a significant public health burden and its incidence is increasing, much has been done to overcome it. Pomegranate (Punica granatum L.) is one of the polyphenol-rich fruits that is widely mentioned in medical folklore. Pomegranate is commonly used to treat common disorders such as diarrhea, abdominal pain, wound healing, bleeding, dysentery, acidosis, microbial infections, infectious and noninfectious respiratory diseases, and neurological disorders. In the current review article, we aimed to summarize the data on the pharmacotherapeutic potentials of pomegranate in ANDs.

Item Type: Article
Keywords: pomegranate Punica granatum L age-related neurological disorders Parkinson's disease (PD) Alzheimer's disease (AD) cardiovascular risk-factors reactive protein concentrations juice pj consumption oxidative stress punica-granatum ellagic acid lipid-peroxidation blood-pressure nervous-system alzheimers-disease Geriatrics & Gerontology Neurosciences & Neurology
Page Range: p. 27
Journal or Publication Title: Frontiers in Aging Neuroscience
Journal Index: ISI
Volume: 14
Identification Number: https://doi.org/10.3389/fnagi.2022.955735
ISSN: 1663-4365
Depositing User: خانم ناهید ضیائی
URI: http://eprints.mui.ac.ir/id/eprint/25280

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