EVALUATION OF FLEXURAL STRENGTH OF DENTURE-BASED MATERIALS REINFORCED WITH AL2O3, SIO2, TIO2, AND ZRO2 NANOPARTICLES: A SYSTEMATIC REVIEW AND META-ANALYSIS

Abstract

Background: With the introduction of nanotechnology in dentistry, the use of nanoparticles to strengthen acrylic resins has received much attention. The aim of the present study was to evaluate the effects of different percentages (1, 2, 3 & 5) of Al2O3, SiO2, TiO2, and ZrO2 nanoparticles in acrylic resin on the bending strength. Materials & Methods: The PRISMA 2020 Checklist was used to carry out a systematic review and meta-analysis as the basis for the current investigation. Up until 23 October 2022, systematic literature searches were conducted on Scopus, PubMed, EBSCO, Web of Science, ISI Web of Knowledge, and Embase. Then, a fixed-effect model and the inverse-variance method were been utilized to generate the 95 confidence interval for mean differences. Data from the meta-analysis has been analyzed utilizing Stata/MP v.17 software. Results: A review of abstracts from 800 studies was conducted in the initial review of the study to eliminate duplicates; full texts of 391 studies were reviewed by two authors, and 14 studies were ultimately chosen. The mean flexural strength difference between the control group and the 1 Al2O3 reinforcement was-6.19 (MD,-6.19 95 CI-8.26,-4.11; p=0.00). The mean flexural strength difference between the control group and the 3 SiO2 reinforcement was 4.58 (MD, 4.58 95 CI 3.61, 5.56; p=0.00). The mean flexural strength difference between the control group and the 1 TiO2 reinforcement was-4.08 (MD,-4.08 95 CI-35.03, 26.87; p=0.80).Conclusions: It can be concluded from the present meta-analysis that the properties of polymers reinforced with nanoparticles depend on their type and concentration.