(2023) Scaffolds: a biomaterial engineering in targeted drug delivery for osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. pp. 255-267. ISSN 1433-2965 (Electronic) 0937-941X (Linking)
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Abstract
Osteoporosis is an increasingly common condition that causes low bone density, porous bone, and increased fracture risk. Treatments for osteoporosis are divided into two categories: (a) antiresorptive and (b) anabolic. To decrease side effects of drug and dosage level variations caused by several consecutive administrations, various drug delivery systems have been proposed. Among them, scaffolds are one of the drug delivery systems that led to drug impart with high loading and suitable efficiency to specific sites which retain active agents at acceptable therapeutic levels. The purpose of this review was to explain the role of scaffolds in targeted drug delivery to bone tissue for the treatment of osteoporosis.
| Item Type: | Article |
|---|---|
| Keywords: | Humans Biocompatible Materials/therapeutic use *Osteoporosis/drug therapy Drug Delivery Systems *Fractures, Bone/drug therapy Bone and Bones *Bone Density Conservation Agents/therapeutic use *Anabolic Agents Biomaterial engineering Drug delivery Osteoporosis Scaffold Targeted |
| Page Range: | pp. 255-267 |
| Journal or Publication Title: | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA |
| Journal Index: | Pubmed |
| Volume: | 34 |
| Number: | 2 |
| Identification Number: | https://doi.org/10.1007/s00198-022-06543-3 |
| ISSN: | 1433-2965 (Electronic) 0937-941X (Linking) |
| Depositing User: | خانم ناهید ضیائی |
| URI: | http://eprints.mui.ac.ir/id/eprint/27810 |
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