Effects of decellularized extracellular matrix on Polyhydroxybutyrate electrospun scaffolds for cartilage tissue engineering

(2023) Effects of decellularized extracellular matrix on Polyhydroxybutyrate electrospun scaffolds for cartilage tissue engineering. Polymer-Plastics Technology and Materials. pp. 771-789. ISSN 25740881 (ISSN)

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Abstract

The current study was carried out to evaluate the effects of cartilage-decellularized extracellular matrix (ECM) on Poly (3-hydroxybutyrate) (PHB) electrospun scaffold for cartilage tissue engineering. In this study, PHB scaffolds with three different percentages of ECM (1, 2, and 3) were fabricated. Mechanical, chemical, and physical properties of scaffolds along with their interactions with cells were assessed. Results showed that by adding of ECM to the scaffolds, the Physiomechanical properties of combined scaffolds were modified, compared to the pure PHB scaffold. In the other hand, the biological behavior was increased by increasing the ECM ratio to the PHB. © 2022 Taylor & Francis.

Item Type: Article
Keywords: Cartilage tissue engineering electrospinning extracellular matrix Poly-3-hydroxybutyrate scaffold Cartilage 'current Chemical and physical properties Decellularized Electrospun scaffolds Extracellular matrices Poly(3-hydroxybutyrate) Poly--3-hydroxybutyrate Polyhydroxybutyrate Scaffolds (biology)
Page Range: pp. 771-789
Journal or Publication Title: Polymer-Plastics Technology and Materials
Journal Index: Scopus
Volume: 62
Number: 6
Identification Number: https://doi.org/10.1080/25740881.2022.2150863
ISSN: 25740881 (ISSN)
Depositing User: خانم ناهید ضیائی
URI: http://eprints.mui.ac.ir/id/eprint/28328

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