Application of amino acid-based natural deep eutectic solvents in extraction of different analytes: A review study

Abstract

Background: Common solvents are mainly volatile organic compounds derived from petroleum, which are harmful to human health and the environment. Reducing the consumption of these toxic solvents or replacing them with safe solvents is vital. Recently, it has suggested the use of green alternative solvents as a proper solution. Scope and approach: The present study reviews various aspects of amino acid-based natural deep eutectic solvents (AABNADESs) from synthesis to application. This investigation can provide a theoretical basis for the extensive application of AABNADESs in extraction of various analytes and also can be a guidance to choose the proper solvent for each analyte. Key findings and conclusions: Amino acid-based deep eutectic solvents are natural plant metabolites with at least one amino acid component that can be synthesized in various physical ways through the formation of hydrogen bonds. These emerging and green solvents are competitive to organic solvents to recover a wide range of analytes and can be a suitable alternative to toxic solvents in the field of extraction due to reasons such as biodegradability, tunable features, and being safe. Adjusting the inherent characteristics of DESs and optimizing other factors are necessary in order to achieve the highest extraction efficiency.