Effects of balloon pulmonary valvuloplasty on longitudinal changes in right ventricular strain and strain rate in pediatric pulmonary stenosis

Abstract

BACKGROUND: Balloon Pulmonary Valvulolasty (BPV) is a procedure for Pulmonary Stenosis (PS) treatment. In this study, right ventricl (RV) performance was determied through 2D-Speckle Tracking Echcardiograhy (2D-STE). METHODS: The study involved 25 diagosed chilren with PS undergoing BPV and 25 normal cildren. They wer examined usng 2D-STE and Linear Mixed Model (LMM) approach was used to deermine changes in Pulmonary Vve Peak Gradient (PVPG), Tiuspid Annular Pane Sysolic Excursion (TAPSE), strin and Strain Rate (SR) for RV, and Ejction Fracton for Left Ventricle (LVEF). RESULTS: Notable differences were found between two groups in TAPSE ( P=0.001 ), global strain ( P=0.001 ), apicl septal strain ( P=0.024 ), middle setal strain ( P=0.001 ), basal sptal sin ( P=0.001 ), apical lateral SR ( P=0.001 ), middle ltral SR ( P=0.007 ), basal lateral SR ( P=0.001 ), and apical septal SR ( P=0.001 ). Post-BPV, there was an increase in LVEF CONCLUSION:(P=0.001) : ( P=0.001 ) and TAPSE ( P=0.001 ) but PVPG decreaed ( P=0.001 ). Follwing BPV, a increase was observed in apical laterl strain ( P=0.004 ), mddle septal strain ( P=0.001 ), apical septal strain ( P=0.003 ), middle septal strain ( P=0.001 ), basal septal strain ( P=0.048 ), apical septal SR ( P=0.025 ), and middle septal SR ( P=0.023 ). Gender was remarkably correlated with mean changes in basal lateral strain ( P=0.019 ), middle septal strain ( P=0.037 ), and middle septal SR Key ord ( P=0.020 ). Age of PS children was related to mean change in basal septal strain ( P=0.031 ) and basal septal SR ( P=0.018 ). CONCLUSION: Strain and SR in RV improved post-BPV in children with PS. The gender and fsbision: 01 O 2019 D f a ep ace 26 Ju 2020 age of the children revealed remarkable effects on RV strain and SR changes after BPV.