Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders

(2024) Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders. Neurochemical Research. pp. 583-596. ISSN 1573-6903 (Electronic) 0364-3190 (Linking)

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Abstract

Neurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in the etiology of neurological disorders. In studies on the genesis of neurological diseases, aquaporin 4 (AQP4) expression and activity have both been linked to ncRNAs. The upregulation or downregulation of several ncRNAs leads to neurological disorder progression by targeting AQP4. The role of ncRNAs and AQP4 in neurological disorders is discussed in this review.

Item Type: Article
Keywords: Humans Aquaporin 4/genetics/metabolism Quality of Life RNA, Untranslated/metabolism *Nervous System Diseases/genetics Down-Regulation *MicroRNAs Aquaporin-4 Long non-coding RNA Neurological disorders Non-coding RNAs microRNA
Page Range: pp. 583-596
Journal or Publication Title: Neurochemical Research
Journal Index: Pubmed
Volume: 49
Number: 3
Identification Number: https://doi.org/10.1007/s11064-023-04067-8
ISSN: 1573-6903 (Electronic) 0364-3190 (Linking)
Depositing User: خانم ناهید ضیائی
URI: http://eprints.mui.ac.ir/id/eprint/30332

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