Intraoperative Magnesium Sulfate Infusion Enhances Neuroprotection and Muscle Relaxation during Brain Tumor Resection: A Case Report

Abstract

Intraoperative neurophysiological monitoring (IONM) is a valuable technique used during brain tumor resections to assess and preserve neurological function. This case report investigates the impact of intraoperative magnesium sulfate infusion on neuroprotection and muscle relaxation in the context of IONM during brain tumor resection. A 48-year-old male with altered awareness and occasional convulsive movements involving his right upper and lower limbs accompanied by progressive right-sided weakness and occasional sensory disturbances was diagnosed with a left temporal lobe tumor. He underwent craniotomy for tumor resection, with concurrent IONM and an intraoperative magnesium sulfate infusion. The patient’s neurophysiological parameters, surgical outcomes, and postoperative recovery were analyzed, suggesting a potential synergistic effect between magnesium sulfate and IONM in optimizing patient outcomes. © 2024, Shiraz University of Medical Sciences. All rights reserved.