Determining the normal range of the dimensions and volume of the pituitary gland of children using a 3D magnetic resonance imaging (MRI) protocol in Imam Hossein Hospital of Isfahan in 2021 to 2024

Abstract

BACKGROUND: Understanding the morphological changes and dimensions of the pituitary gland is crucial for accurate diagnosis and personalized treatment in pediatric patients. Advanced imaging techniques, such as 3D magnetic resonance imaging (MRI), enhance our ability to address knowledge gaps and improve clinical practices in pediatric endocrinology. This study aims to determine normative pituitary gland dimensions and volumes in pediatric patients at Imam Hossein Hospital in Isfahan using advanced 3D MRI protocols. METHODS: Conducted as a prospective cross-sectional study, this research focused on children under 15 years without specific conditions. A total of 412 participants were selected through simple random sampling, and data were analyzed using SPSS version 20 to rigorously assess measurements and extract insights beneficial for pediatric endocrinology. RESULTS: The study included participants aged 0 to 15 years, with a higher representation of boys (63.83) compared to girls (36.17). Significant differences were observed in height and volume based on gender and age group. Scatterplots illustrated variations in the pituitary gland's volume, width, height, and anterior-posterior diameter according to age and gender. CONCLUSION: This research provides valuable insights into pediatric endocrinology, facilitating accurate diagnosis and treatment of pituitary disorders in children.