Evaluation of Relative Frequency of Pathogens of Patients Admitted to PICU Ward and Their Antibiotic Resistance Pattern in Imam Hossein Pediatric Hospital in Isfahan

Abstract

Background: Early diagnosis of disease-causing bacteria and predicting their response to antibiotics is one of the necessities of serving patients related to infectious diseases; Based on this, the study was conducted to determine the relative frequency of pathogens of patients admitted to the PICU ward and their antibiotic resistance patterns in Imam Hossein Pediatric Hospital in Isfahan. Methods: This cross-sectional study was conducted between September 2018 and September 2019 at Imam Hossein (AS) Children's Hospital in Isfahan included children aged 1 to 21 years admitted to the hospital's PICU who had positive culture samples. Data were obtained from patient medical records. Frequency distribution and percentages were used to describe the data. Findings: According to the findings of the study, the frequency of gram-negative bacteria was higher than gram-positive bacteria, and Staphylococcus epidermidis was the most common gram-positive bacteria with 14.66 and E. coli with 14.2 was the most common gram-negative bacteria. Conclusion: Antibiotic resistance is a significant healthcare system problem associated with negative consequences in dealing with infectious diseases. The findings of this study are useful for treatment areas and hospitals that are related to such diseases. © 2025, Isfahan University of Medical Sciences(IUMS). All rights reserved.