Prevalence of Infection Associated with Central Venous Catheter and the Type of Pathogen and Its Related Factors in the Intensive Care Units of Ayatollah Kashani Hospital in Isfahan

Abstract

Background: Catheter mortality and cost of care related to catheter infection and hospitalization are among the cases that clarify the importance of further studies in this field. Therefore, the aim of this study was to investigate the frequency of catheter-related infections. The central vein and the type of pathogen and its related factors were in the intensive care units of Ayatollah Kashani Hospital. Methods: This cross-sectional study evaluated the rate of infection caused by central venous catheter in 78 patients admitted to the intensive care unit. Catheter implantation time, ICU length of stay, catheter location, disease severity was assessed using APACHE II criteria during catheter placement, type of antibiotic used. After collecting data using Chi-square test and frequency distribution table and related graphs at the error level of 0.05 was performed using SPSS software version 26. Findings: Less than half of the patients (44.9) showed central venous catheter infection. Also, more than half of the patients had gram-positive pathogens (52.6) and the rest had gram-negative pathogens. There was a significant difference between gender, age and time of hospitalization, patients and the incidence of central venous catheter infection (P <0.05). There was no significant difference between underlying diseases, disease severity using APACHE II criterion and type of antibiotic used with CRI in patients (P > 0.05). Frequency of CRI by location (femoral, jugular, subclavian) was observed in patients with central venous catheter admitted to ICU (P <0.05) and the highest rate of central venous catheter infection was related to subclavian location (51.4). Conclusion: Lack of hygiene by medical staff is the most important factor in the incidence of infection caused by central venous catheter. Factors such as underlying disease, disease severity, and type of antibiotic used do not affect central venous catheter infection. The best location is the catheter, jugular and femoral. © 2025, Isfahan University of Medical Sciences(IUMS). All rights reserved.