The Relationship between Type D Personality and Blood Groups Subtypes, and Medication Adherence in Iranian Patients with Type II Diabetes Mellitus

Abstract

Background: The aim of this study was to investigate the relationship between blood groups and personality types, and medication adherence in Type 2 Diabetes Mellitus (T2DM). Methods: 302 patients with T2DM were considered in the study. Their sociodemographic information and medical history were recorded. Type D personality and medical adherence were checked using DS-14 and MMAS-8 questionnaires, respectively. Blood samples were obtained from the patients to determine the types of ABO blood groups, HbA1c, fasting blood sugar and lipid profile. Results: No significant association was found between the patients’ characteristics including demographic and laboratory information and medical adherence to treatment. However, a significant difference in medical adherence was observed between patients with type D personality. According to logistic regression model, patients with type D OR: 6.23, (95%CI: 2.34-16.55, p<0.001 had better adherence to medication, while the blood groups was not associated with medical adherence to treatment. Conclusion: Type D personality cannot impair medical adherence in these patients. There was an association between type D personality and the ABO blood group, but the ABO blood group was not related to medical adherence. © 2026, Islamic Republic of Iran Medical Council. All rights reserved.