Interdigital intertrigo due to Fusarium oxysporum

Abstract

BACKGROUND AND PURPOSE: Fusariosis is a fungal infection often involving the skin. Various species can cause local, focally invasive, or disseminated infections. The routes of entry for Fusarium species include the respiratory tract, gastrointestinal tract, toe nails, trauma to the skin, and indwelling central venous catheter. CASE REPORT: Herein, we present the case of a 35-year-old woman presenting with interdigital intertrigo. The patient had no predisposing factors and she did not take any antifungal agents. Fusiform macroconidia were observed on the slide culture of the fungus. The etiological agent of the infection was identified as Fusarium oxysporum through sequencing of the translation elongation factor-1 alpha (TEF-1alpha) gene using the primers EF1 and EF2. CONCLUSION: Fusariosis commonly presents as a severe fungal infection in immunocompromised patients. However, this infection may also occur in immunocompetent patients. Although treatment with amphotericin B is a routine antifungal therapy for fusariosis, many azoles such as cloterimazole can be used topically with fewer side-effects.