The relationship of erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) with an uncertain prognosis for the patients admitted to the intensive care unit in Alzahra hospital, Isfahan, Iran, during 2014-2015

Abstract

Background: This study aimed to the relationship of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) with an uncertain prognosis for the patients admitted to the intensive care unit (ICU) in Alzahra Hospital, Isfahan, Iran, during 2014-2015. Methods: In a cross-sectional study, 100 patients admitted in intensive care units of Alzahra hospital were selected and within five days, C-reactive protein level and erythrocyte sedimentation rate were measured. In addition, all the patients were studied for incidence of delirium. Findings: During 5 days of hospitalization, 46 patients were suffering from delirium. The mean erythrocyte sedimentation rate in the two groups with and without delirium was 9.11 � 2.00 and 8.73 � 2.02 millimeter per hour, respectively, and there was no significant difference between the two groups (P = 0.340). Mean serum C-reactive protein level in two groups with and without delirium was 12.20 � 6.06 and 9.55 � 4.27, respectively (P = 0.012). Conclusion: Changes in the level of inflammatory markers such as C-reactive protein in patients during hospitalization in intensive care units, especially in the first days of hospitalization and in the elderly, can be a good indicator for predicting the incidence of delirium. But, considering the differences in various studies, we recommend that more studies with larger sample sizes should be conducted. � 2016, Isfahan University of Medical Sciences(IUMS). All rights reserved.