Investigation of mean platelet volume among patients with sudden sensorineural hearing loss

Abstract

Background: Sudden sensorineural hearing loss (SSNHL) refers to the condition in which sudden hearing loss happens and mostly occurs when waking in the morning and is followed by progressive hearing loss within 12 hours or less. SSNHL due to rapid accordance is comorbid to psychological reaction in about 90 of patients. Although SSNHL is idiopathic, some studies show a relation between platelet volume and this disease. The aim of this study was to compare the platelet volume between patients with SSNHL patients and a control group. Methods: In a case control study, during 2012-2013, 55 patients with SSNHL and 55 healthy persons were selected and serum level of mean platelete volume (MPV), wight blood cell (WBC), red blood cell (RBC) and platelet was compared between the two groups. Findings: The mean of MPV in the case and control group was 8.93 ± 0.96 and 9.55 ± 0.99 and the difference between the two groups was statistically significant (P < 0.001). Also, the level of WBC and RBC in case groups was higher than the control groups (P > 0.050). Conclusion: According to the results of this study, the high level of platelet, MPV and hematocrit probably have an effect on SSNHL, which should be mediated. However, another study with a larger sample size is recommended. © 2016, Isfahan University of Medical Sciences(IUMS). All rights reserved.