(2015) 3-Keto umbilicagenin A and B, new sapogenins from Allium umbilicatum Boiss. Fitoterapia. pp. 198-202. ISSN 0367-326X
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Abstract
Two sapogenins, named 3-keto umbilicagenin A and B (1 and 2), possessing a novel chemical structure with a 3-keto group on the spirostane skeleton, have been isolated from Allium umbilicatum Boiss. Their chemical structure has been established through a combination of extensive spectroscopic analysis, mainly nuclear magnetic resonance and mass spectrometry, and chemical methods as (25R)-3-keto-spirostan-2 alpha,5 alpha,6 beta-triol (1) and (25R)-3-keto-spirostan-2 alpha,5 alpha-diol (2). The isolated compounds were tested for cytotoxic activity on J-774, murine monocyte/macrophage, and WEHI-164, murine fibrosarcoma cell lines. (C) 2015 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Keywords: | allium steroidal sapogenins 3-keto spirostanol nmr cytotoxic activity antiproliferative sapogenins antifungal saponins steroidal saponins persian leek bulbs porrum glycosides spirostane nutrition furostane |
| Page Range: | pp. 198-202 |
| Journal or Publication Title: | Fitoterapia |
| Journal Index: | ISI |
| Volume: | 102 |
| Identification Number: | https://doi.org/10.1016/j.fitote.2014.12.016 |
| ISSN: | 0367-326X |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.mui.ac.ir/id/eprint/4979 |
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