Seroprevalence of toxoplasmosis in mentally retarded patients in Iranian rehabilitation centers

Abstract

Toxoplasma gondii is one of the most common causes of latent infections in humans and animals. Although T. gondii infection is widely prevalent in the world, most acquired cases of the disease are asymptomatic. The important aspect of this parasitic infection is the probable danger of congenital transmission and its severe effects on the fetus. There have been many reports about the prevalence of anti-T. gondii antibody among different groups of people in Iran; however the epidemiological data in mentally retarded patients are rare. The present study was conducted on 158 mentally retarded persons (94 males, 64 females) in the rehabilitation centers of Khoramabad from autumn 2012 to winter 2013. The overall prevalence of anti-T. gondii antibody was 30.4 (48 cases). There were no significant difference between sex and toxoplasmosis (p > 0.05). However, there were no statistically significant difference between age and toxoplasmosis, nevertheless the prevalence of toxoplasmosis in the patients less than 10-years-old had significantly the lowest rate. The highest infection rates were found in the two age groups of 10-19 and >/=30 years old. Our results showed that the prevalence of toxoplasmosis in the mentally retarded persons in the rehabilitation centers of Khorramabad was similar to the prevalence in pregnant women in this city. Therefore, the disease does not cause additional danger to this group of women.