(2015) Echinophora platyloba DC. as a new natural antifungal agent. Asian Pacific Journal of Tropical Disease. pp. 169-174. ISSN 22221808 (ISSN)
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Abstract
Echinophora platyloba DC. (Umbelliferae family) (E. platyloba) is a spiny plant with yellow flowers that in Iranian traditional medicine is used as an antifungal agent for preventing the dairy products and foods from fungi contaminations. This subject was the basis of an idea that has been supposed E. platyloba as an antifungal agent. This review investigates the studies that are designed on this idea. Also, it mentions other investigations that evaluate the other biological activities of this valuable plant. Literatures about E. platyloba were collected by electronic search and referred books on ethnopharmacology for receiving traditional records about this plant. Although, E. platyloba is a plant with many pharmacological effects but the main biological effect is their antifungal and synergistic effect with azole drugs against Candida albicans infections in vitro and in vivo studies. E. platyloba can be used as new candidates for treatment of Candida albicans infections. Other pharmacological effects should be more evaluated. Future studies should be directed on isolation and identification of antifungal sub-fractions by more precise investigations. © 2015 by the Asian Pacific Journal of Tropical Disease.
| Item Type: | Article |
|---|---|
| Keywords: | Biological activity Candida albicans Echinophora platyloba Iranian traditional medicine 3 carene amphotericin B antifungal agent ascorbic acid carvacrol cefalexin clotrimazole cloxacillin cresol Echinophora platyloba extract essential oil fluconazole itraconazole limonene miconazole ocimene penicillin G phenol derivative placebo plant extract pyrrole derivative thymol unclassified drug agar dilution antibacterial activity antibiotic sensitivity antifungal activity antioxidant activity antiprotozoal activity Apiaceae Article broth dilution candidiasis dairy product drug antagonism drug efficacy drug identification drug isolation drug potentiation drug safety dysmenorrhea ethnopharmacology evening dosage food contamination free radical scavenging assay fungal contamination human hydrodistillation IC50 in vitro study in vivo study Iran LD 50 minimal fungicidal concentration minimum inhibitory concentration nonhuman pharmacological parameters phytochemistry premenstrual syndrome randomized controlled trial (topic) solvent extraction toxicity testing traditional medicine treatment duration Trichomonas vaginalis vaginitis |
| Page Range: | pp. 169-174 |
| Journal or Publication Title: | Asian Pacific Journal of Tropical Disease |
| Journal Index: | Scopus |
| Volume: | 5 |
| Number: | 3 |
| Identification Number: | https://doi.org/10.1016/S2222-1808(14)60647-2 |
| ISSN: | 22221808 (ISSN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.mui.ac.ir/id/eprint/6277 |
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