Remedial effect of Boswellia serrata on thermal burn injuries

Abstract

Background: It has been shown that inflammation and insufficient blood vessel formation delay wound healing, whereas Boswellia serrata, besides anti-inflammatory activity, increases blood vessel formation. Objectives: This study was performed to investigate the effect of Boswellia serrata in promoting burn injuries healing in BALB/c mice. Materials and Methods: In this experimental study, a burn wound was created by placing a 1.5 cm2 hot plate on the back of animals. Fifty four mice were designated in four equal groups, counting 14 each. Three groups of animals were treated with Boswellia 2, silver sulfadiazine and vaseline two times per day for 21 days. The fourth group represented the control group. The total percentage of wound healing and time required for complete healing were evaluated and compared between groups, using the ANOVA test. Results: Results showed that the effect of Boswellia on wound healing was statistically significant compared to the control group (P < 0.01). Conclusions: Boswellia serrata is clearly effective for burn injuries healing and might be used in patients with burn wound. © 2015, Shiraz University of Medical Sciences.