Role of granulocyte colony-stimulating factor in human reproduction

(2018) Role of granulocyte colony-stimulating factor in human reproduction. Journal of Research in Medical Sciences. ISSN 1735-1995

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Abstract

As new research reveals, granulocyte colony-stimulating factor (G-CSF) plays an effective role in pregnancy success, considering that it not only affects the embryo implantation and ovarian function but also it promotes endometrial thickening and improves the pathophysiology of endometriosis, which all fundamentally lead to reducing pregnancy loss. In this review, we focus on the role of G-CSF in human reproduction. We summarized its role in ovulation, luteinized unruptured follicle syndrome, poor responders, improving repeated in vitro fertilization failure, endometrial receptivity and treatment of thin endometrium, and recurrent spontaneous abortion.

Item Type: Article
Keywords: fertilization in vitro granulocyte colony-stimulating factor habitual abortion ovulation in-vitro fertilization recurrent implantation failure follicular g-csf thin endometrium embryo-transfer infertile women clinical pregnancy randomized-trial poor responders cycles
Divisions: Faculty of Medicine > Departments of Clinical Sciences > Department of Obstetrics and Gynecology
Journal or Publication Title: Journal of Research in Medical Sciences
Journal Index: ISI
Volume: 23
Identification Number: ARTN 7 10.4103/jrms.JRMS₆₂₈₁₇
ISSN: 1735-1995
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/6537

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