Correlation Between Resistin Level and Metabolic Syndrome Component: A Review

(2018) Correlation Between Resistin Level and Metabolic Syndrome Component: A Review. Hormone and Metabolic Research. pp. 521-536. ISSN 0018-5043

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Abstract

Metabolic syndrome (MetS) has a collection of some abnormal and pathological conditions that cause many critical diseases. Resistin is one of the possible candidates for these pathologies but there are not enough data to prove if resistin has positive, neutral, or negative effects on one or some components of MetS. This review summarizes data about comparing the effects and contribution of resistin in initiation and progression of MetS components and also its different actions between human and other mammalians. This summarized data about the relationship of resistin and MetS components have been obtained from clinical researches and in some cases even animal studies. To find the relevant studies, the search in PubMed, Science Direct, and Scopus were performed. Human and animal studies on relationships between resistin and MetS (initiation and progression of components) were included in our search. In experiments reported among different human genetic groups as well as the patients with various disease such as diabetes, no significant correlation is shown between FBG and resistin level. Furthermore, this review shows that the results of correlation between resistin and TG, HDL, and central or abdominal obesity were inconsistent. These inconsistencies can arise from different sample size or genetic groups, gender, and also from experimental studies. Therefore, to obtain precise results systematic review and meta-analyses are required.

Item Type: Article
Keywords: correlation resistin metabolic syndrome coronary-artery-disease fatty liver-disease cyclase-associated protein-1 adipose-tissue compartments type-2 diabetes-mellitus increased serum resistin c-reactive protein insulin-resistance plasma resistin risk-factors
Divisions: Cardiovascular Research Institute
Cardiovascular Research Institute > Isfahan Cardiovascular Research Center
Page Range: pp. 521-536
Journal or Publication Title: Hormone and Metabolic Research
Journal Index: ISI
Volume: 50
Number: 7
Identification Number: https://doi.org/10.1055/a-0637-1975
ISSN: 0018-5043
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/6806

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