Clinical and Epidemiological Aspects of Multiple Sclerosis in Children

(2017) Clinical and Epidemiological Aspects of Multiple Sclerosis in Children. Iranian Journal of Child Neurology. pp. 37-43. ISSN 1735-4668

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Abstract

Objective Overall, 2-5 of patients with multiple sclerosis (MS) experienced the first episode of disease before the age 18 years old. Since the age of onset among children is not similar to that in general population, clinicians often fail to early diagnose the disease. This study aimed to determine the epidemiological and clinical patterns of MS among Iranian children. Materials & Methods In this cross-sectional study carried out in Iran in 2014-2015, information was collected using a checklist with approved reliability and validity. Method sampling was consensus. Data were analyzed using frequency, mean and standard deviation indices by means of SPSS ver. 20 software. Results Totally, 177 MS children were investigated. 75.7 of them were female. Mean (SD), minimum and maximum age of subjects were 15.9 (2), 7 and 18 yr, respectively. The most reported symptoms were sensory (28.2), motor (29.4), diplopia (20.3) and visual (32.8). Primary MRI results showed 91.5 and 53.1 periventricular and spinal cord lesions, respectively. Conclusion MS is significantly more common among women. The most common age of onset is during the second decades. Sensory and motor problems are the most symptoms, while, periventricular and spinal cord lesions are the most MRI results.

Item Type: Article
Keywords: multiple sclerosis children epidemiology clinical iran risk-factors isfahan onset iran
Divisions: Faculty of Medicine > Departments of Clinical Sciences > Department of Neurology
Page Range: pp. 37-43
Journal or Publication Title: Iranian Journal of Child Neurology
Journal Index: ISI
Volume: 11
Number: 2
ISSN: 1735-4668
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mui.ac.ir/id/eprint/694

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