Investigation of clinicopathological parameters in emergency colorectal cancer surgery: a study of 67 patients

(2017) Investigation of clinicopathological parameters in emergency colorectal cancer surgery: a study of 67 patients. Archives of Medical Science. pp. 1394-1398. ISSN 1734-1922

Full text not available from this repository.

Abstract

Introduction: The aim of the present study was to establish, having adjusted for case mix, the size of the differences in postoperative mortality and 5-year survival between patients presenting as an emergency with evidence of obstruction and perforation and the association of clinicopathological factors with mortality (bivariate analyses). Material and methods: The study included 67 patients who presented with colorectal cancer (CRC) between 2009 and 2013 in Iran. The mean age of the patients was 59.7 years. Of the 67 patients, 37 (55.22) were male and 30 (44.77) were female. Certain parameters that correlated with CRC and surgical treatment were investigated Results: Our results showed that 46 (68.65) patients had obstruction, while perforation was observed in 21 (31.34) cases. Among the patients with obstruction, obstruction of the right colon was observed in 29 (43.28) cases. There was no significant difference in mortality rate between right and left colonic obstruction. Based on the bivariate analyses, our findings showed that death of patients was significantly related to tumor grade (p = 0.02) and TNM staging (p = 0.026), but no association was found between other parameters and death, including age, sex, and tumor site. Conclusions: Compared with patients who undergo elective surgery for colon cancer, those who present as an emergency with evidence of obstruction or perforation have higher postoperative mortality rates and poorer cancer-specific survival. Also, colorectal cancer patients with emergency surgery showed aggressive histopathology and an advanced stage.

Item Type: Article
Keywords: colorectal cancers emergency surgery histopathological factors survival large-bowel obstruction colon-carcinoma epidemiology prognosis mortality patterns survival lesions trends risk
Divisions: Faculty of Medicine > Departments of Clinical Sciences > Department of Emergency medicine
Page Range: pp. 1394-1398
Journal or Publication Title: Archives of Medical Science
Journal Index: ISI
Volume: 13
Number: 6
Identification Number: https://doi.org/10.5114/aoms.2016.61385
ISSN: 1734-1922
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mui.ac.ir/id/eprint/868

Actions (login required)

View Item View Item