Electrospun polycaprolactone/gelatin/bioactive glass nanoscaffold for bone tissue engineering

(2019) Electrospun polycaprolactone/gelatin/bioactive glass nanoscaffold for bone tissue engineering. International Journal of Polymeric Materials and Polymeric Biomaterials. pp. 607-615. ISSN 0091-4037

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Abstract

Polycaprolactone scaffolds, polycaprolactone/gelatin, and polycaprolactone/gelatin/bioactive glass scaffolds were prepared with ratios of 50/50, 25/75, and 75/25 for polymers and 5 wt for the bioactive glass via electrospinning and then were characterized using. The results indicated that by adding gelatin and bioactive glass to polycaprolactone scaffold, the diameter of fiber decreased from 557 to 167 nm. The results showed growth of apatite layer on the scaffolds after immersion in simulated body fluid for 28 days. The results of mechanical test revealed that by adding bioactive glass to scaffolds, the ultimate tensile strength and Young's modulus increase about two folds.

Item Type: Article
Keywords: bioactivity bone tissue engineering degradation behavior electrospun scaffold mechanical properties nanocomposite bioactive glass scaffolds hydroxyapatite fabrication nanofibers gelatin solvent
Divisions: Biosensor research center
Other
Page Range: pp. 607-615
Journal or Publication Title: International Journal of Polymeric Materials and Polymeric Biomaterials
Journal Index: ISI
Volume: 68
Number: 10
Identification Number: https://doi.org/10.1080/00914037.2018.1482461
ISSN: 0091-4037
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/9945

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