Items where Author is "Sirous, H."

Article

(2025) Targeting N-Methyl-lysine Histone Demethylase KDM4 in Cancer: Natural Products Inhibitors as a Driving Force for Epigenetic Drug Discovery. ChemMedChem. e202400682. ISSN 1860-7187 (Electronic) 1860-7179 (Print) 1860-7179 (Linking)

(2024) Dihydropyrimidine derivatives as MDM2 inhibitors. Chemical Biology and Drug Design. ISSN 17470277 (ISSN)

(2024) Discovery of novel direct small-molecule inhibitors targeting HIF-2alpha using structure-based virtual screening, molecular dynamics simulation, and MM-GBSA calculations. Molecular diversity. pp. 1203-1224. ISSN 1573-501X (Electronic) 1381-1991 (Linking)

(2024) Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study. Daru-Journal of Pharmaceutical Sciences. pp. 599-615.

(2024) New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots. Daru-Journal of Pharmaceutical Sciences. pp. 237-251.

(2024) A bioinformatics approach of specificity protein transcription factors in head and neck squamous cell carcinoma. Research in Pharmaceutical Sciences. pp. 287-302. ISSN 1735-5362

(2023) Disruption of Irisin Dimerization by FDA-Approved Drugs: A Computational Repurposing Approach for the Potential Treatment of Lipodystrophy Syndromes. International Journal of Molecular Sciences. p. 23. ISSN 1661-6596

(2023) Exosomes as efficient platforms for delivering adenosine-tetra peptide conjugate to pancreatic cancer cells: An <i>in vitro/in silico</i> study. Journal of Drug Delivery Science and Technology. p. 14. ISSN 1773-2247

(2023) In Silico Identification of Natural Products and World-Approved Drugs Targeting the KEAP1/NRF2 Pathway Endowed with Potential Antioxidant Profile. Computation. p. 27.

(2023) Integrative bioinformatics analysis of ACS enzymes as candidate prognostic and diagnostic biomarkers in colon adenocarcinoma. Research in Pharmaceutical Sciences. pp. 413-429. ISSN 1735-5362

(2023) Preparing a database of corrected protein structures important in cell signaling pathways. Research in Pharmaceutical Sciences. pp. 67-77. ISSN 1735-5362

(2023) Pyrimido 4,5-b indole derivatives bearing 1,2,4-oxadiazole moiety as MDM2 inhibitor candidates in cancer treatment. Future Medicinal Chemistry. pp. 517-532. ISSN 1756-8919

(2023) Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulation for the Discovery of Novel SARS-CoV-2 NSP3 Mac1 Domain Inhibitors. Viruses-Basel. p. 21.

(2022) Design, synthesis, and cytotoxicity evaluation of novel indole-acylhydrazone derivatives of 4-pyridinone as potential histone deacetylase-2 inhibitors. Research in Pharmaceutical Sciences. pp. 572-584. ISSN 1735-5362

(2022) Expression analysis of HIF-3a as a potent prognostic biomarker in various types of human cancers: a case of meta-analysis. Research in Pharmaceutical Sciences. pp. 508-526. ISSN 1735-5362

(2021) Discovery of novel hit compounds as potential HDAC1 inhibitors: The case of ligand- and structure-based virtual screening. Comput Biol Med. ISSN 0010-4825 1879-0534 J9 - COMPUT BIOL MED

(2016) In vitro and in silico studies of the inhibitory effects of some novel kojic acid derivatives on tyrosinase enzyme. Iranian Journal of Basic Medical Sciences. pp. 132-144. ISSN 2008-3866

(2015) Design, synthesis and anti-HIV-1 evaluation of a series of 5-hydroxypyridine-4-one derivatives as possible integrase inhibitors. Medicinal Chemistry Research. pp. 4113-4127. ISSN 1054-2523

(2015) Docking studies of some 5-hydroxypyridine-4-one derivatives: evaluation of integrase and ribonuclease H domain of reverse transcriptase as possible targets for anti-HIV-1 activity. Medicinal Chemistry Research. pp. 2195-2212. ISSN 1054-2523