Evaluation of physical, mechanical, and biodegradation of chitosan/graphene oxide composite as bone substitutes

Abstract

In this study, a nanocomposite was prepared from chitosan (Cs) and graphene oxide (GO) with different percentages. The results of Fourier-transform infrared spectroscopy, thermal gravity analysis, and X-ray diffraction showed that the presence of GO nanoparticles increased thermal stability and crystallinity of Cs. Tensile test results showed that the presence of 0.3 wt. GO in Cs film increased the tensile strength and Young's modulus by 296 and 193, respectively. The results of bioactivity and biodegradation test showed that the presence of GO in Cs film increased the density of the apatite-like layer on the surface and the degradation time. GRAPHICS .